Volume 10, Issue 4 (2025)                   SJMR 2025, 10(4): 209-225 | Back to browse issues page


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Shafti1 V, Azarboo A, Javidan A. Clinical Outcomes and Complications of Extraperitoneal Caesarean Section: A Systematic Review and Network Meta-Analysis. SJMR 2025; 10 (4) : 7
URL: http://saremjrm.com/article-1-384-en.html
1- School of Medicine, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran.
2- School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Abstract:   (173 Views)
Background: Various cesarean delivery approaches have been developed to accelerate postpartum recovery and reduce perioperative and postoperative complications. The aim of this study was to compare the clinical outcomes and complications of ECS and TCS for cesarean delivery. Additionally, we investigated different techniques employed in ECS itself to find the best method of CS.
Methods: A PRISMA-guided systematic search was conducted on electronic databases to identify studies from 1945 to 2023. Studies comparing extraperitoneal cesarean section (ECS) and transperitoneal cesarean section (TCS) for cesarean delivery constituted the included population. Observational and RCT studies were included, with a focus on surgical outcomes, complications, and postoperative recovery. The quality of manuscripts was assessed using the CONSORT and Newcastle-Ottawa scales. Hedges' g standardized mean differences (SMD) and Mantel-Haenszel risk ratio (RR) were used for data synthesis. Network meta-analysis was also performed to compare ECS techniques.
Results: A systematic review and meta-analysis of 698 potential studies on extraperitoneal Caesarean sections (ECS) and transperitoneal cesarean sections (TCS) found no significant difference in total operation time. However, the French AmbUlatory Cesarean Section (FAUCS) method showed longer operation times, while classical paravesical ECS showed shorter times. ECS patients experienced greater blood loss but no significant difference in hemoglobin change. ECS patients were associated with a higher risk of intra-operative vomiting and nausea, while TCS patients reported higher post-operative pain levels. ECS patients had a faster recovery of gastrointestinal function, but the risk of urinary tract infection was comparable between ECS and TCS. When considering RCTs, CONSORT indicated variations in the completeness and quality of reporting in these trials. For the observational studies, the majority received scores of 8 or 9, demonstrating a consistent and relatively high level of methodological quality in these study designs.
Conclusions: This update provides reproductive clinicians and scientists with valuable insights into the clinical outcomes and complications associated with extraperitoneal cesarean sections. By comparing different approaches and their effects on surgical outcomes, pain management, and complications, this study informs clinical practice, helping clinicians make more informed decisions and potentially improve patient care.

 
Article number: 7
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Article Type: Original Research | Subject: Childbirth
Received: 2026/01/6 | Accepted: 2026/02/14 | Published: 2026/03/12

References
1. 1. Martin JA, Hamilton BE, Osterman MJK, Driscoll AK. Births: Final Data for 2018. Natl Vital Stat Rep. 2019;68(13):1-47.
2. Corso E, Hind D, Beever D, Fuller G, Wilson MJ, Wrench IJ, et al. Enhanced recovery after elective caesarean: a rapid review of clinical protocols, and an umbrella review of systematic reviews. BMC Pregnancy Childbirth. 2017;17(1):91. [DOI:10.1186/s12884-017-1265-0] [PMID] []
3. Shafti V, Azarboo A, Ghaemi M, Gargari OK, Madineh E. Prediction of intraperitoneal adhesions in repeated cesarean sections: A Systematic review and Meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2023;287:97-108. [DOI:10.1016/j.ejogrb.2023.05.039] [PMID]
4. Dimassi K, Ami O, Fauck D, Simon B, Velemir L, Triki A. French ambulatory cesarean: Mother and newborn safety. Int J Gynaecol Obstet. 2020;148(2):198-204. [DOI:10.1002/ijgo.13013] [PMID]
5. Bačić B, Hrgović Z, Cerovac A, Barčot O, Sabljić J, Markoski B, et al. Comparison between extraperitoneal and transperitoneal cesarean section: Retrospective case-control study. Z Geburtshilfe Neonatol. 2025;229(3):188-94. [DOI:10.1055/a-2338-5802] [PMID]
6. Sharma PP, Gond S, Ansari MDK, Madhuri N, Bera SN. Extraperitoneal cesarean section: a retrospective analysis. International journal of reproduction, contraception, obstetrics and gynecology. 2020;9:1089. [DOI:10.18203/2320-1770.ijrcog20200880]
7. Tappauf C, Schest E, Reif P, Lang U, Tamussino K, Schoell W. Extraperitoneal versus transperitoneal cesarean section: a prospective randomized comparison of surgical morbidity. Am J Obstet Gynecol. 2013;209(4):338.e1-8. [DOI:10.1016/j.ajog.2013.05.057] [PMID]
8. Yapca OE, Topdagi YE, Al RA. Fetus delivery time in extraperitoneal versus transperitoneal cesarean section: a randomized trial. J Matern Fetal Neonatal Med. 2020;33(4):657-63. [DOI:10.1080/14767058.2018.1499718] [PMID]
9. Hibbard LT. Extraperitoneal cesarean section. Clin Obstet Gynecol. 1985;28(4):711-21. [DOI:10.1097/00003081-198528040-00004] [PMID]
10. Perkins RP. Role of extraperitoneal cesarean section. Clin Obstet Gynecol. 1980;23(2):583-99. [DOI:10.1097/00003081-198006000-00026] [PMID]
11. Dimassi K, Halouani A, Kammoun A, Ami O, Simon B, Velemir L, et al. The extraperitoneal French AmbUlatory cesarean section technique leads to improved pain scores and a faster maternal autonomy compared with the intraperitoneal Misgav Ladach technique: A prospective randomized controlled trial. PLoS One. 2021;16(1):e0245645. [DOI:10.1371/journal.pone.0245645] [PMID] []
12. Ji C, Chen M, Qin Y. Evaluation of clinical practice of extraperitoneal cesarean section. Research Square; 2022. [DOI:10.21203/rs.3.rs-1708395/v1]
13. Sagi S, Bleicher I, Bakhous R, Pelts A, Talhamy S, Caspin O, et al. Comparison between the modified French AmbUlatory Cesarean Section and standard cesarean technique-a randomized double-blind controlled trial. Am J Obstet Gynecol MFM. 2023;5(7):100910. [DOI:10.1016/j.ajogmf.2023.100910] [PMID]
14. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097. [DOI:10.1371/journal.pmed.1000097] [PMID] []
15. Babita P. Vaswani AT, Sriram Gopal. Extraperitoneal versus transperitoneal cesarean section: a retrospective analysis. 2020;9(2). [DOI:10.18203/2320-1770.ijrcog20200337]
16. Bebincy D. S.* CJ. Extraperitoneal versus transperitoneal cesarean section in surgical morbidity in a tertiary care centre. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2017;6(8). [DOI:10.18203/2320-1770.ijrcog20173450]
17. Erenel CYH. Extraperitoneal versus transperitoneal cesarean section: a retrospective analysis. Perinatal Journal. 2017;25:38-42. [DOI:10.2399/prn.17.0251008]
18. Karaaslan O, Türkyılmaz G, Şimşek E. Extraperitoneal cesarean, is it safe and comfortable? Eastern J Med. 2020;25(4):530-4. [DOI:10.5505/ejm.2020.78790]
19. Senturk MB, Kilicci C, Doğan O, Yenidede I, Polat M, Pulatoğlu Ç, et al. Comparison of extra-peritoneal and intra-peritoneal cesarean technique: a prospective randomised trial. CEOG. 2018;45(5):756-61. [DOI:10.12891/ceog4403.2018]
20. Wallace RL, Eglinton GS, Yonekura ML, Wallace TM. Extraperitoneal cesarean section: a surgical form of infection prophylaxis? Am J Obstet Gynecol. 1984;148(2):172-7. [DOI:10.1016/S0002-9378(84)80171-4] [PMID]
21. Ying GAO. Extraperitoneal cesarean section versus transabdominal caesarean section for pain situation of puerperas. Journal of Clinical Medicine in Practice. 2018(23):76-8.
22. Atherton HE, Williamson PJ. A clinical comparison of extraperitoneal cesarean section and low cervical cesarean section for the potentially or frankly infected parturient. Am J Obstet Gynecol. 1954;68(4):1091-7. [DOI:10.1016/S0002-9378(16)38404-6] [PMID]
23. Hanson HB. Current use of the extraperitoneal cesarean section: A decade of experience. American Journal of Obstetrics and Gynecology. 1984;149(1):31-4. [DOI:10.1016/0002-9378(84)90288-6] [PMID]
24. Shinde G, Pawar A, Jadhav B, Rathod K. Modified extraperitoneal Caesarean section: clinical experience. Trop Doct. 2012;42(4):188-90. [DOI:10.1258/td.2012.120241] [PMID]
25. Wells G, Shea B, O'Connell D, Peterson j, Welch V, Losos M, et al. The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Non-Randomized Studies in Meta-Analysis. ᅟ. 2000;ᅟ.
26. Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25(9):603-5. [DOI:10.1007/s10654-010-9491-z] [PMID]
27. Schulz KF, Altman DG, Moher D. CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. Trials. 2010;11:32. [DOI:10.1186/1745-6215-11-32] [PMID] []
28. Lin L, Aloe AM. Evaluation of various estimators for standardized mean difference in meta-analysis. Stat Med. 2021;40(2):403-26. [DOI:10.1002/sim.8781] [PMID] []
29. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. Bmj. 2003;327(7414):557-60. [DOI:10.1136/bmj.327.7414.557] [PMID] []
30. Lin L, Chu H. Quantifying publication bias in meta-analysis. Biometrics. 2018;74(3):785-94. https://doi.org/10.1111/biom.12815 [DOI:10.1111/biom.12817] []
31. Rouse B, Chaimani A, Li T. Network meta-analysis: an introduction for clinicians. Intern Emerg Med. 2017;12(1):103-11. [DOI:10.1007/s11739-016-1583-7] [PMID] []
32. COSGROVE SA, NORTON JF. CESAREAN SECTION: INDICATIONS FOR AND RELATIVE MERITS OF THE CLASSIC, LOW AND EXTRAPERITONEAL OPERATIONS. Journal of the American Medical Association. 1942;118(3):201-4. [DOI:10.1001/jama.1942.02830030019004]
33. Wylie BJ, Gilbert S, Landon MB, Spong CY, Rouse DJ, Leveno KJ, et al. Comparison of transverse and vertical skin incision for emergency cesarean delivery. Obstet Gynecol. 2010;115(6):1134-40. [DOI:10.1097/AOG.0b013e3181df937f] [PMID] []
34. Olyaeemanesh A, Bavandpour E, Mobinizadeh M, Ashrafinia M, Bavandpour M, Nouhi M. Comparison of the Joel-Cohen-based technique and the transverse Pfannenstiel for caesarean section for safety and effectiveness: A systematic review and meta-analysis. Med J Islam Repub Iran. 2017;31:54. [DOI:10.14196/mjiri.31.54] [PMID] []
35. Davies J, Davies D. Origins and evolution of antibiotic resistance. Microbiol Mol Biol Rev. 2010;74(3):417-33. [DOI:10.1128/MMBR.00016-10] [PMID] []
36. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet. 2022;399(10325):629-55. [DOI:10.1016/S0140-6736(21)02724-0] [PMID] []
37. Yang XJ, Sun SS. Comparison of maternal and fetal complications in elective and emergency cesarean section: a systematic review and meta-analysis. Arch Gynecol Obstet. 2017;296(3):503-12. [DOI:10.1007/s00404-017-4445-2] [PMID]
38. Darnal N, Dangal G. Maternal and Fetal Outcome in Emergency versus Elective Caesarean Section. J Nepal Health Res Counc. 2020;18(2):186-9. [DOI:10.33314/jnhrc.v18i2.2093] [PMID]
39. Pan J, Hei Z, Li L, Zhu D, Hou H, Wu H, et al. The Advantage of Implementation of Enhanced Recovery After Surgery (ERAS) in Acute Pain Management During Elective Cesarean Delivery: A Prospective Randomized Controlled Trial. Ther Clin Risk Manag. 2020;16:369-78. [DOI:10.2147/TCRM.S244039] [PMID] []
40. Soergel P, Jensen T, Makowski L, von Kaisenberg C, Hillemanns P. Characterisation of the learning curve of caesarean section. Arch Gynecol Obstet. 2012;286(1):29-33. [DOI:10.1007/s00404-012-2230-9] [PMID]
41. Fok WY, Chan LY, Chung TK. The effect of learning curve on the outcome of caesarean section. Bjog. 2006;113(11):1259-63. [DOI:10.1111/j.1471-0528.2006.01060.x] [PMID]
42. Waalewijn BP, van Duinen A, Koroma AP, Rijken MJ, Elhassein M, Bolkan HA. Learning Curve Characteristics for Caesarean Section Among Associate Clinicians: A Prospective Study from Sierra Leone. World J Surg. 2017;41(12):2998-3005. [DOI:10.1007/s00268-017-4202-5] [PMID]

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