Volume 7, Issue 4 (2022)
SJMR 2022, 7(4): 209-215 |
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Hassani Bafrani M, Amini Mahabadi A, Hassani Bafrani H. Effect of diet containing sesame seeds on testis and prostate of adult Wistar rats. SJMR 2022; 7 (4) : 2
URL: http://saremjrm.com/article-1-276-en.html
URL: http://saremjrm.com/article-1-276-en.html
1- Student Research Committee, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
2- Responsible for administrative affairs, Payame Noor University, Ardestan, Isfahan, Iran.
3- Full Professor of Anatomical Science, Gametogenesis Research Center, Kashan University of Medical Sciences, Kashan, Iran.
2- Responsible for administrative affairs, Payame Noor University, Ardestan, Isfahan, Iran.
3- Full Professor of Anatomical Science, Gametogenesis Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Abstract: (3023 Views)
Introduction: Studies show that some antioxidants are effective in improving male infertility. Sesame is one of the main lignan components of sesame seeds and is considered as a key factor in a number of beneficial effects on human health. It has been shown that the consumption of sesame leaves improves and increases the storage of epididymal spermatocytes in adult male Sprague Dawley rats. Considering several antioxidant compounds in sesame seeds, this study was designed and conducted with the aim of the effect of sesame seed diet on the structure of testis and prostate along with sex hormones of adult male rats.
Material and methods: This experimental study was conducted on 30 adult 200 gr Wistar rats that were obtained from the Laboratory Animal Center of Kashan University of Medical Sciences. Mice were randomly divided into two experimental and control groups. The control group received standard diet and the experimental group received diet containing 70% standard diet and 30% sesame seeds after weaning for 12 weeks. At the end of the study, the weight and volume of the testes were measured, and the spermatogenic tubes, diameter of the epithelium lumen, LH, FSH and testosterone concentration were evaluated. The prostates of mice were examined after being fixed. The data was analyzed using SPSS software and t-test. P<0.05 was considered significant.
Results: The body weight of mice, the weight and volume of the testes and the percentage of the volume of the vessels of seminiferous tubules were not significant in two groups. The average number of cells and sperm motility in the left epididymis, the number of epithelial cells and the percentage of epithelial, lumen and interstitial volume of these tubes in the experimental group were highly significant (P<0.0001). The concentration of LH in the experimental group increased significantly compared to the control group (P<0.03). According to the results of this study, the diameter of the peripheral epithelium of the prostate showed a significant increase in the test group compared to the control group with a probability level (P<0.05), but no significant difference was observed in the diameter of the central epithelium between the test groups. The volume density of the prostate epithelium of the experimental group compared to the control rats showed significant changes.
Conclusion: Sesame consumption improved testicular parameters, fertility and sperm production in men. Consuming sesame seeds improved sperm parameters and increased LH levels; but it had no effect on the body weight of the mice. Also, sesame seeds improve the reproductive system of male rats through testis and prostate histopathology.
Material and methods: This experimental study was conducted on 30 adult 200 gr Wistar rats that were obtained from the Laboratory Animal Center of Kashan University of Medical Sciences. Mice were randomly divided into two experimental and control groups. The control group received standard diet and the experimental group received diet containing 70% standard diet and 30% sesame seeds after weaning for 12 weeks. At the end of the study, the weight and volume of the testes were measured, and the spermatogenic tubes, diameter of the epithelium lumen, LH, FSH and testosterone concentration were evaluated. The prostates of mice were examined after being fixed. The data was analyzed using SPSS software and t-test. P<0.05 was considered significant.
Results: The body weight of mice, the weight and volume of the testes and the percentage of the volume of the vessels of seminiferous tubules were not significant in two groups. The average number of cells and sperm motility in the left epididymis, the number of epithelial cells and the percentage of epithelial, lumen and interstitial volume of these tubes in the experimental group were highly significant (P<0.0001). The concentration of LH in the experimental group increased significantly compared to the control group (P<0.03). According to the results of this study, the diameter of the peripheral epithelium of the prostate showed a significant increase in the test group compared to the control group with a probability level (P<0.05), but no significant difference was observed in the diameter of the central epithelium between the test groups. The volume density of the prostate epithelium of the experimental group compared to the control rats showed significant changes.
Conclusion: Sesame consumption improved testicular parameters, fertility and sperm production in men. Consuming sesame seeds improved sperm parameters and increased LH levels; but it had no effect on the body weight of the mice. Also, sesame seeds improve the reproductive system of male rats through testis and prostate histopathology.
Article number: 2
Keywords: hj
Article Type: Brief Communication |
Subject:
Childbirth
Received: 2023/01/6 | Accepted: 2023/03/1 | Published: 2023/07/15
Received: 2023/01/6 | Accepted: 2023/03/1 | Published: 2023/07/15
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