Aims: Ovulation induction is one of the main steps in assisted reproductive technology (ART). Ovarian hyperstimulation syndrome (OHSS) is a serious complication of ART. The patients with polycystic ovary (PCO) are at higher risk for OHSS when they are subjected to such techniques. The objective of this study was to investigate the pregnancy outcomes of mild and moderate OHSS in PCO and non-PCO patients.
Materials and Methods: This retrospective cross-sectional study was carried out on 321 OHSS patients candidate for IVF/ICSI based on their medical records in Sarem Women’s Hospital (Tehran, Iran) in a period of two years. The general characteristics of the patients and the parameters related to pregnancy were compared between the group of PCO and non-PCO patients. Data were analyzed by Fisher exact test and T-test using SPSS 13 software.
Findings: A significant difference was found in hospitalization periods between PCO and non-PCO groups (p=0.002). The PCO group showed higher level of OHSS severity compared to the non-PCO group (p=0.0001). The number of transferred embryo had significant difference between PCO and non-PCO groups (p=0.015). There was no significant difference in clinical pregnancy success rate between PCO (11.8%) and non-PCO (14.2%) patients (p=0.602).
Conclusion: In OHSS patients, the overall pregnancy success rate is lower than normal. The PCO background is not a determining factor for the pregnancy success rate in the patients with OHSS. A similar pregnancy success rate can be achieved by longer duration of treatment for OHSS and more number of transmitted embryos in individuals with PCO.