Introduction: In the Qajar era, some hospitals were established with personal funds for the welfare of people, one of which was Vaziri Hospital. In this article, for the enrichment and authenticity of the contents, the author tried to use all available first-hand references, especially historical documents available in the National Library and Archives of the Islamic Republic of Iran in order to write the history of the establishment, development, and activities of Vaziri Hospital and commemorate Mirza Isa Vazir and Sheikh Hadi Najm Abadi, two philanthropist in the medical services in Iran.
Conclusion: Vaziri Hospital was founded by Sheikh Hadi Najm Abadi, using the endowments of Mirza Isa Vazir; during 97 years (from 1897 to 1994), thousands of patients benefited from its health care. Mirza Isa, known as "Vazir," after being affected by cholera in 1889, decided to establish a hospital to improve the health and fight against diseases, and before his death, he made a will to Sheikh Hadi Njambaladi to establish a hospital by one-third of his property, but due to disputes occurred among the heirs of Mirza Isa, this action did not become practical until 1894. In the middle of 1894, Sheikh Hadi resolved the disputes and chose a land of 4000 square meters in the current location of Vaziri Hospital according to the will to establish the hospital; the construction continued until 1897.