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Nateghi M R, Sanaye Naderi M, Mohammadian H. Ovarian Tissue Cryopreservation: Advances, Challenges, and Future Perspectives in Fertility PreservationFollowing Heterotopic Grafting. SJMR 2025; 10 (3) : 6
URL: http://saremjrm.com/article-1-378-en.html
Ovarian Tissue Cryopreservation: Advances, Challenges, and Future Perspectives in Fertility PreservationFollowing Heterotopic Grafting
Mohammad Reza Nateghi *1 , Maryam Sanaye Naderi1 , Hadis Mohammadian1
1- Sarem Gynecology, Obstetrics and Infertility Research Center, Sarem Women’s Hospital, Iran University of Medical Sciences, Tehran, Iran. & Sarem Cell Research Center (SCRC), Sarem Women’s Hospital, Tehran, Iran.
Abstract:   (76 Views)
Introduction: Fertility preservation is a primary concern for women of reproductive age, particularly for those undergoing medical treatments such as chemotherapy or radiation therapy. These treatments can have negative impacts on the ovaries and egg reserve. Therefore, methods such as ovarian tissue freezing have emerged as a way to preserve fertility in these individuals. Ovarian tissue freezing is especially promising in cases where mature eggs cannot be collected. This technique involves the removal of ovarian tissue, freezing it, and utilizing it for future transplantation. This review article aims to examine the advances and challenges associated with this method and explore its future potential in the medical field.
Conclusion: Ovarian tissue freezing is currently considered an effective and safe method for preserving fertility in women undergoing medical treatments. Despite significant advancements in freezing and thawing techniques, challenges such as the survival rate and functionality of the tissue after transplantation still exist. However, ongoing research and studies are continuously improving these methods, and it is expected that this technique will become a standard approach for fertility preservation, particularly in specific medical conditions, in the future.
Article number: 6
Keywords: Ovarian Tissue Freezing, Infertility, Freezing and Thawing Techniques, Ovarian Transplantation.
Full-Text [PDF 647 kb]   (55 Downloads)    
Article Type: Analytical Review | Subject: Women Diseases
Received: 2025/10/5 | Accepted: 2025/10/15 | Published: 2025/10/25
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