Volume 10, Issue 1 (2025)
SJMR 2025, 10(1): 11-15 |
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Nateghi M R, Sanaye Naderi M, Mohammadian H. Association Between Body Mass Index (BMI) and Oocyte and Embryo Quality Indicators in Patients Undergoing Assisted Reproductive Treatment at Sarem Women Hospital, Tehran. SJMR 2025; 10 (1) : 3
URL: http://saremjrm.com/article-1-345-en.html
URL: http://saremjrm.com/article-1-345-en.html
1- Sarem Gynecology, Obstetrics and Infertility Research Center, Sarem Women’s Hospital, Iran University of Medical Sciences, Tehran, Iran. & Sarem Cell Research Center (SCRC), Sarem Women’s Hospital, Tehran, Iran.
Abstract: (542 Views)
Introduction: Body mass index (BMI) is considered a potential factor influencing the success of assisted reproductive technologies (ART), including in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). Given the increasing prevalence of obesity, assessing the relationship between BMI and gamete and embryo quality is of growing clinical interest. Therefore, the aim of this study was association between BMI and oocyte and embryo quality indicators in patients undergoing assisted reproductive treatment at Sarem fertility hospital, Tehran.
Materials and Methods: In this cross-sectional analytical study, 462 infertile women who referred to Sarem Specialized Hospital in Tehran were evaluated. Participants were divided into four BMI categories: underweight, normal, overweight, and obese. Variables including the number of retrieved oocytes, oocyte and embryo quality, number of embryos transferred, implantation rate, insulin resistance, and dysmenorrhea were recorded and analyzed using SPSS. A p-value of less than 0.05 was considered statistically significant.
Results: No statistically significant differences were observed among the BMI groups in terms of infertility type, insulin resistance, dysmenorrhea, number of oocytes, oocyte grading, embryo quality, or implantation rate (P>0.05). Overall, BMI showed no significant impact on the quantitative or qualitative parameters of oocytes and embryos in this study.
Discussion: In contrast to some previous studies that associate higher BMI with poorer gamete and embryo quality, the findings of this study suggest that BMI alone is not a reliable predictor of oocyte or embryo quality. Future research with longitudinal design and better control of confounding variables is recommended to clarify these associations.
Materials and Methods: In this cross-sectional analytical study, 462 infertile women who referred to Sarem Specialized Hospital in Tehran were evaluated. Participants were divided into four BMI categories: underweight, normal, overweight, and obese. Variables including the number of retrieved oocytes, oocyte and embryo quality, number of embryos transferred, implantation rate, insulin resistance, and dysmenorrhea were recorded and analyzed using SPSS. A p-value of less than 0.05 was considered statistically significant.
Results: No statistically significant differences were observed among the BMI groups in terms of infertility type, insulin resistance, dysmenorrhea, number of oocytes, oocyte grading, embryo quality, or implantation rate (P>0.05). Overall, BMI showed no significant impact on the quantitative or qualitative parameters of oocytes and embryos in this study.
Discussion: In contrast to some previous studies that associate higher BMI with poorer gamete and embryo quality, the findings of this study suggest that BMI alone is not a reliable predictor of oocyte or embryo quality. Future research with longitudinal design and better control of confounding variables is recommended to clarify these associations.
Article number: 3
Article Type: Analytical Review |
Subject:
Women Diseases
Received: 2025/04/27 | Accepted: 2025/05/19 | Published: 2025/06/8
Received: 2025/04/27 | Accepted: 2025/05/19 | Published: 2025/06/8
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