Volume 8, Issue 4 (2023)
SJMR 2023, 8(4): 277-286 |
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Solhi S, Sadat Firouzeh F, Tahmasebizadeh M, Akrami Z, Karami S, Lotfi Y et al . Challenges and solutions for the management of drug-resistant Nosocomial infections. SJMR 2023; 8 (4) : 8
URL: http://saremjrm.com/article-1-303-en.html
URL: http://saremjrm.com/article-1-303-en.html
Sara Solhi1 
, Farhat Sadat Firouzeh2 , Mobina Tahmasebizadeh3 , Zahra Akrami3 , Sina Karami2 , Yavar Lotfi4 , Mohammad Esmaeil Amini *5
, Farhat Sadat Firouzeh2 , Mobina Tahmasebizadeh3 , Zahra Akrami3 , Sina Karami2 , Yavar Lotfi4 , Mohammad Esmaeil Amini *5
1- Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- Student Research Committee, Kashan University of Medical Sciences, Kashan, Iran
3- Student Research Committee, Ardabil University of Medical Sciences, Ardabil, Iran
4- Student Research Committee, Lorestan University
5- Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran ,moh.es.amini@gmail.com
2- Student Research Committee, Kashan University of Medical Sciences, Kashan, Iran
3- Student Research Committee, Ardabil University of Medical Sciences, Ardabil, Iran
4- Student Research Committee, Lorestan University
5- Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran ,
Abstract: (1272 Views)
In hospitals, healthcare-associated infections (HAI), also referred as nosocomial infections (NI), pose a significant challenge, leading to prolonged hospitalization, increased healthcare costs, and mortality. Pathogens can be transmitted through high-touched surfaces, healthcare worker hands, and contaminated medical equipment. These infections are often caused by Multi-Drug Resistance Organisms (MDROs), which are bacteria resistant to multiple antimicrobial agents. Patients with higher illness severity scores, older age, and longer ICU stays are at increased risk. The most common side effect of healthcare is nosocomial infections, which can happen in any setting. Bacterial, fungal, and viral infections are potential causes for them, spread through direct or indirect contact. MRDOs, such as Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant Enterococci (VRE), and bacteria that produce Extended-spectrum beta-lactamases (ESBLs), pose a significant problem because of their antibiotic resistance. Preventive measures such as air filtration, hand hygiene, and environmental cleaning are important. Enhanced hand cleanliness, implementing contact precautions, and surveillance are crucial in managing MDROs. It is essential to use antibiotics judiciously and implement appropriate clinical measures. Further research is necessary to combat the proliferation of resistant strains. In conclusion, nosocomial infections caused by MDROs have significant public health implications. Effective prevention, control, and diagnosis are crucial in managing these infections. Preventive measures and proper antibiotic use are essential in controlling the spread of resistant bacteria.
Article number: 8
Article Type: Analytical Review |
Subject:
Health and safety
Received: 2023/12/22 | Accepted: 2024/02/4 | Published: 2024/11/27
Received: 2023/12/22 | Accepted: 2024/02/4 | Published: 2024/11/27
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