Volume 7, Issue 1 (2022)                   SJMR 2022, 7(1): 15-23 | Back to browse issues page

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Nateghi M R, Sanaye Naderi M, Saremi A. Vertical transmission of Covid-19 disease through mother to neonate: A cross-sectional study. SJMR 2022; 7 (1) : 2
URL: http://saremjrm.com/article-1-252-en.html
1- Sarem gynecology, Obstetrics and Infertilty Research Center, Sarem Women's Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran. & Sarem Cell Research Center (SCRC), Sarem Women’s Hospital, Tehran, Iran.
2- Sarem gynecology, Obstetrics and Infertilty Research Center, Sarem Women's Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran. & Sarem Cell Research Center (SCRC), Sarem Women’s Hospital, Tehran, Iran. , saremcr@gmail.com
Abstract:   (1208 Views)
Introduction: The new coronavirus, known as Covid-19, is a highly contagious disease that is spread through the respiratory droplets of infected people. Vertical transmission is the transmission of an infectious pathogen from mother to fetus in the prenatal and postpartum period or to the infant during the postpartum period through intrauterine placenta, contact of body fluids during childbirth or through direct contact due to postpartum breastfeeding. The aim of this study was investigation of vertical transmission of the disease through mother to infant.
Material and methods: In this cross-sectional study, 117 patients participated in the study. All pregnant women had positive RT-PCR results for SARS-CoV-2 RNA. Nasopharyngeal and Oropharyngeal swabs were used to detect Covid-19 infection. To perform umbilical cord blood sampling, a sterile needle was inserted through the vagina and 10 cc of amniotic fluid was carefully inserted under sterile conditions just before rupture of the membranes and before leakage. Data were statistically analyzed using SPSS software version 24.
Results: Among the 5 cases of positive cord blood test compared to the negative cases of this test, there was no difference between the gender of the newborns (P>0.05). The average weight of babies with positive umbilical cord blood was 3067.46 grams and in babies with negative umbilical cord blood, it was 3588 grams, and a statistically significant difference was observed between these two groups (P<0.05). Also, there was no statistically significant difference between the two groups including positive and negative cord blood tests and parameters such as gender, height, weight, heart rate, breathing rate and Apgar scores of one and five minutes of newborns (P>0.05).

Conclusion: of 117 births, only 6 babies were infected with the Covid-19 virus and the height of the babies infected with this virus was lower than the babies born to healthy mothers. It is possible that the low height of the baby at birth indicates the transmission of this virus from the mother to the baby, but with this small number of infected babies, it cannot be pointed out with certainty.
Article number: 2
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Article Type: Original Research | Subject: Women Diseases
Received: 2022/04/17 | Accepted: 2022/06/5 | Published: 2023/01/8

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