Volume 2, Issue 3 (2017)                   SJMR 2017, 2(3): 159-163 | Back to browse issues page


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Saremi A, Roomandeh N, Sanaye Naderi M, Younesi B, Lashgari P, Zare A. Evaluation of serum zinc levels in women with recurrent spontaneous abortion. SJMR 2017; 2 (3) :159-163
URL: http://saremjrm.com/article-1-45-en.html
1- “Sarem Fertility & Infertility Research Center (SAFIR)” and “Sarem Cell Research Center (SCRC)”, Sarem Women’s Hospital, Tehran, Iran Women’s Hospital, Tehran, Iran
2- Sarem Fertility & Infertility Research Center (SAFIR), Sarem Women’s Hospital, Tehran, Iran
3- Sarem Women’s Hospital, Tehran, Iran
4- “Sarem Fertility & Infertility Research Center (SAFIR)” and “Sarem Cell Research Center (SCRC)”, Sarem Women’s Hospital, Tehran, Iran Women’s Hospital, Tehran, Iran , azare@razi.tums.ac.ir
Abstract:   (8875 Views)

Aims: Recurrent spontaneous abortion (RSA) is defined as three or more consecutive pregnancy failure before the 20th week of gestation affecting approximately 1 in 300 pregnant women. The element, Zinc, is involved in both the embryonic development and the function of the mother's immune system, so its deficiency may affect the normal process of pregnancy. The objective of this study was to investigate the serum zinc levels in patients with RSA.
Materials & Methods: This study was conducted on patients with RSA who referred to Sarem women’s hospital (Tehran, Iran). The sera samples were obtained from 243 non-pregnant women with at least three RSA and 73 non-pregnant women as a control and then were stored at -20°C. Zinc concentrations were measured by using an atomic absorption spectrophotometry system. The data were analyzed by SPSS 16 using Mann-Whitney U test.
Findings: Serum zinc level in women with a history of RSA was 68.13±11.43 μg/dl, which was significantly lower than those in normal controls with mean zinc concentration of 82.90±12.36 μg/dl (p<0.05).
Conclusion: The level of zinc in the serum of women with RSA is lower than that of healthy women. Zinc deficiency may be one of the factors that contribute to miscarriage.

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Article Type: Original Research | Subject: Sterility
Received: 2016/04/15 | Accepted: 2016/08/20 | Published: 2017/10/21

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