Volume 9, Issue 2 (2024)
SJMR 2024, 9(2): 59-66 |
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Ethics code: IR.ZUMS.REC.1400.321
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jozpanahi M, Jalili N, Aghamohammadi M, Seifi Alan M, Hamzelou L. Studying the frequency of acute renal failure in patients with COVID-19 hospitalized in Mousavi and Valiasr hospitals in Zanjan. SJMR 2024; 9 (2) : 2
URL: http://saremjrm.com/article-1-323-en.html
URL: http://saremjrm.com/article-1-323-en.html
Manizheh Jozpanahi1 
, Nooshin Jalili *2 , Mehdi Aghamohammadi3 , Mahin Seifi Alan1 , Leila Hamzelou1
, Nooshin Jalili *2 , Mehdi Aghamohammadi3 , Mahin Seifi Alan1 , Leila Hamzelou1
1- Department of Infectious Disease, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
2- Department of Internal Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran ,Dr.nooshinjalili@zums.ac.ir
3- Department of Internal Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
2- Department of Internal Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran ,
3- Department of Internal Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Abstract: (526 Views)
Introduction: One of the severe complications of COVID-19 is acute kidney injury (AKI), which can increase the risk of mortality. The present study investigates the prevalence of AKI in patients hospitalized with COVID-19. Examining the complications of this disease is helpful in treatment and prognosis determination.
Materials and Methods: This research was a cross-sectional study. A total of 308 patients with PCR-positive COVID-19 who were hospitalized from 21 February 2020 to 21 February 2021 in Vali Asr and Mousavi hospitals in Zanjan were included in the study. The diagnosis of acute kidney injury was confirmed based on specific criteria (an increase in serum creatinine by at least 0.3 mg/dL within 48 hours or an increase of more than 50% from baseline within one week) and by reviewing the information recorded in the patients' files.
Findings: The incidence of AKI was observed in 90 patients (29.2%). Ninety-one patients (29.5%) were admitted to the ICU. Additionally, this study showed a significant relationship between the occurrence of AKI and factors such as older age, male gender, prolonged hospitalization, GFR below 60, decreased O2 saturation, severe lung involvement, history of hypertension, chronic kidney disease, and ICU admission among patients.
Conclusion: COVID-19 infection leads to an increased incidence of acute kidney injury, and the kidneys are among the organs at risk during this disease. It is recommended that patients with severe COVID-19 who experience significant arterial oxygen desaturation and have a lower than normal GFR, as well as individuals with a history of kidney problems, be monitored for renal disorders during and after their illness.
Materials and Methods: This research was a cross-sectional study. A total of 308 patients with PCR-positive COVID-19 who were hospitalized from 21 February 2020 to 21 February 2021 in Vali Asr and Mousavi hospitals in Zanjan were included in the study. The diagnosis of acute kidney injury was confirmed based on specific criteria (an increase in serum creatinine by at least 0.3 mg/dL within 48 hours or an increase of more than 50% from baseline within one week) and by reviewing the information recorded in the patients' files.
Findings: The incidence of AKI was observed in 90 patients (29.2%). Ninety-one patients (29.5%) were admitted to the ICU. Additionally, this study showed a significant relationship between the occurrence of AKI and factors such as older age, male gender, prolonged hospitalization, GFR below 60, decreased O2 saturation, severe lung involvement, history of hypertension, chronic kidney disease, and ICU admission among patients.
Conclusion: COVID-19 infection leads to an increased incidence of acute kidney injury, and the kidneys are among the organs at risk during this disease. It is recommended that patients with severe COVID-19 who experience significant arterial oxygen desaturation and have a lower than normal GFR, as well as individuals with a history of kidney problems, be monitored for renal disorders during and after their illness.
Article number: 2
Article Type: Original Research |
Subject:
Health and safety
Received: 2024/07/20 | Accepted: 2024/08/20 | Published: 2024/12/9
Received: 2024/07/20 | Accepted: 2024/08/20 | Published: 2024/12/9
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