Volume 10, Issue 2 (2025)                   SJMR 2025, 10(2): 53-55 | Back to browse issues page


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Saremi A. Novel Screening Strategies for Selective Stem Cell Inhibitors: A New Therapeutic Pathway for Endometriosis. SJMR 2025; 10 (2) : 1
URL: http://saremjrm.com/article-1-366-en.html
Sarem Gynecology, Obstetrics and Infertility Research Center, Sarem Women’s Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran. & Sarem Cell Research Center (SCRC), Sarem Women’s Hospital, Tehran, Iran.
Abstract:   (36 Views)
Abstract: Endometriosis is an estrogen-dependent disorder characterized by the presence and growth of endometrial-like tissue outside the uterine cavity, affecting approximately 10% of women of reproductive age [1]. Hormonal agents such as gonadotropin-releasing hormone analogs, oral contraceptives, and progestins are commonly used in its treatment. These therapies alleviate pelvic pain and reduce lesion size; however, recurrence occurs in 30–60% of patients within 3–5 years after treatment cessation [2].
Article number: 1
Full-Text [PDF 214 kb]   (16 Downloads)    
Article Type: Letter to Editor | Subject: Women Diseases
Received: 2025/06/26 | Accepted: 2025/07/6 | Published: 2025/08/12

References
1. 1. Bedaiwy, M.A., et al., New developments in the medical treatment of endometriosis. Fertil Steril, 2017. 107(3): p. 555-565. [DOI:10.1016/j.fertnstert.2016.12.025] [PMID]
2. Grandi, G., et al., Hormonal contraception in women with endometriosis: a systematic review. Eur J Contracept Reprod Health Care, 2019. 24(1): p. 61-70. [DOI:10.1080/13625187.2018.1550576] [PMID]
3. Kimura, N., et al., Novel screening approach for stem cell selective inhibitors and their possible translational therapeutic potential for endometriosis. Reprod Biol, 2025. 25(1): p. 100992. [DOI:10.1016/j.repbio.2024.100992] [PMID]
4. Dawood, S., L. Austin, and M. Cristofanilli, Cancer stem cells: implications for cancer therapy. Oncology (Williston Park), 2014. 28(12): p. 1101-7, 1110.
5. Hong, I.S., Endometrial Stem Cells: Orchestrating Dynamic Regeneration of Endometrium and Their Implications in Diverse Endometrial Disorders. Int J Biol Sci, 2024. 20(3): p. 864-879. [DOI:10.7150/ijbs.89795] [PMID] []
6. Golebiewska, A., et al., Critical appraisal of the side population assay in stem cell and cancer stem cell research. Cell Stem Cell, 2011. 8(2): p. 136-47. [DOI:10.1016/j.stem.2011.01.007] [PMID]
7. Boesch, M., D. Wolf, and S. Sopper, Optimized Stem Cell Detection Using the DyeCycle-Triggered Side Population Phenotype. Stem Cells Int, 2016. 2016: p. 1652389. [DOI:10.1155/2016/1652389] [PMID] []

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