Volume 10, Issue 2 (2025)
SJMR 2025, 10(2): 65-70 |
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Naderi M, Sanaye Naderi M, Mohammadian H. Association between Body Mass Index (BMI) and Sex Hormones in Women Referred to Sarem Women Hospital, Tehran. SJMR 2025; 10 (2) : 3
URL: http://saremjrm.com/article-1-365-en.html
URL: http://saremjrm.com/article-1-365-en.html
1- Sarem Gynecology, Obstetrics and Infertility Research Center, Sarem Women’s Hospital, Iran University of Medical Sciences, Tehran, Iran. & Sarem Cell Research Center (SCRC), Sarem Women’s Hospital, Tehran, Iran. , saremcrc@gmail.com
2- Sarem Gynecology, Obstetrics and Infertility Research Center, Sarem Women’s Hospital, Iran University of Medical Sciences, Tehran, Iran. & Sarem Cell Research Center (SCRC), Sarem Women’s Hospital, Tehran, Iran.
2- Sarem Gynecology, Obstetrics and Infertility Research Center, Sarem Women’s Hospital, Iran University of Medical Sciences, Tehran, Iran. & Sarem Cell Research Center (SCRC), Sarem Women’s Hospital, Tehran, Iran.
Abstract: (33 Views)
Background: Obesity is a growing global health concern associated with multiple metabolic and endocrine disturbances. Among these, alterations in the hypothalamic-pituitary-gonadal (HPG) axis and sex hormone levels are less explored, especially in Middle Eastern populations. This study aimed to investigate the association between body mass index (BMI) and serum sex hormone levels in women referred to Sarem Subspecialty Hospital in Tehran, Iran.
Methods: In this cross-sectional analytical study, data from 462 women aged 20 to 52 years were collected from hospital records. BMI was calculated based on measured height and weight, and participants were classified into four groups. Levels of hormones AMH, FSH, LH, E2, and TSH were measured using standard laboratory methods. The data were analyzed using the ANOVA statistical test.
Results: The mean age of the participants was 36.47±6.45 years, and their mean BMI was 26.18±5.07 kg/m². Statistical analysis showed that with increasing BMI, the levels of LH, FSH, and AMH decreased; however, no significant differences were observed (P>0.05). Additionally, no significant statistical differences were found between different BMI groups in terms of estradiol and TSH levels (P>0.05).
Conclusion: The findings of this study indicate that an increase in body mass index does not have a significant or substantial effect on the balance of sex hormones. On the other hand, given the increasing prevalence of obesity, further and more comprehensive studies on the impact of body mass index on the sex hormone system are necessary.
Methods: In this cross-sectional analytical study, data from 462 women aged 20 to 52 years were collected from hospital records. BMI was calculated based on measured height and weight, and participants were classified into four groups. Levels of hormones AMH, FSH, LH, E2, and TSH were measured using standard laboratory methods. The data were analyzed using the ANOVA statistical test.
Results: The mean age of the participants was 36.47±6.45 years, and their mean BMI was 26.18±5.07 kg/m². Statistical analysis showed that with increasing BMI, the levels of LH, FSH, and AMH decreased; however, no significant differences were observed (P>0.05). Additionally, no significant statistical differences were found between different BMI groups in terms of estradiol and TSH levels (P>0.05).
Conclusion: The findings of this study indicate that an increase in body mass index does not have a significant or substantial effect on the balance of sex hormones. On the other hand, given the increasing prevalence of obesity, further and more comprehensive studies on the impact of body mass index on the sex hormone system are necessary.
Article number: 3
Article Type: Analytical Review |
Subject:
Reproduction
Received: 2025/07/15 | Accepted: 2025/08/1 | Published: 2025/08/12
Received: 2025/07/15 | Accepted: 2025/08/1 | Published: 2025/08/12
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