Volume 7, Issue 4 (2022)
SJMR 2022, 7(4): 259-269 |
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Vafaei A, Farid M, Mehrabani Natanzi M, Khodaii Z. Effect of Probiotic Dairy Consumption on Obesity and Overweight: A Systematic Review and Meta-Analysis. SJMR 2022; 7 (4) : 8
URL: http://saremjrm.com/article-1-283-en.html
URL: http://saremjrm.com/article-1-283-en.html
1- Student Research Committee, Alborz University of Medical Sciences, Karaj, Iran
2- Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran
3- Dietary Supplements and Probiotic Research Center, Alborz University of Medical Sciences, Karaj, Iran & Evidence-based Phytotherapy and Complementary Medicine Research Center, Alborz University of Medical Sciences, Karaj, Iran
4- Dietary Supplements and Probiotic Research Center, Alborz University of Medical Sciences, Karaj, Iran ,zkhodaii@yahoo.com
2- Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran
3- Dietary Supplements and Probiotic Research Center, Alborz University of Medical Sciences, Karaj, Iran & Evidence-based Phytotherapy and Complementary Medicine Research Center, Alborz University of Medical Sciences, Karaj, Iran
4- Dietary Supplements and Probiotic Research Center, Alborz University of Medical Sciences, Karaj, Iran ,
Abstract: (1134 Views)
Background: This systematic review and meta-analysis aim to comprehensively evaluate the effect of probiotic dairy consumption on obesity and overweight individuals.
Methods: A systematic search was conducted across electronic databases to identify relevant clinical trials published between 2000 and 2021. A total of 35 studies met the inclusion criteria, comprising randomized controlled trials assessing the impact of probiotic-containing dairy products on body mass index (BMI), weight, and waist circumference. Random-effects meta-analysis was employed to calculate the Standardized Mean Difference (SMD) and 95% Confidence Intervals (CI) for each outcome.
Results: The pooled analysis of all studies indicated a significant positive association between the consumption of probiotic-containing dairy products and BMI (SMD: 0.30, 95% CI: 0.11-0.50, P<0.001). Subsequent sensitivity analyses confirmed the consistent relationship after excluding heterogeneous studies. Probiotic dairy consumption also exhibited a significant effect on weight (SMD: 0.10, 95% CI: 0.00-0.20, P<0.001) and waist circumference (SMD: 0.44, 95% CI: 0.17-0.71, P<0.001).
Conclusion: This comprehensive meta-analysis provides robust evidence supporting the potential beneficial impact of probiotic-containing dairy products on BMI, weight, and waist circumference in individuals with obesity and overweight. These findings underscore the value of incorporating probiotics into dietary interventions aimed at addressing these challenging public health issues. Further research is warranted to elucidate the mechanisms underpinning these effects and to optimize the implementation of probiotics in clinical practice.
Methods: A systematic search was conducted across electronic databases to identify relevant clinical trials published between 2000 and 2021. A total of 35 studies met the inclusion criteria, comprising randomized controlled trials assessing the impact of probiotic-containing dairy products on body mass index (BMI), weight, and waist circumference. Random-effects meta-analysis was employed to calculate the Standardized Mean Difference (SMD) and 95% Confidence Intervals (CI) for each outcome.
Results: The pooled analysis of all studies indicated a significant positive association between the consumption of probiotic-containing dairy products and BMI (SMD: 0.30, 95% CI: 0.11-0.50, P<0.001). Subsequent sensitivity analyses confirmed the consistent relationship after excluding heterogeneous studies. Probiotic dairy consumption also exhibited a significant effect on weight (SMD: 0.10, 95% CI: 0.00-0.20, P<0.001) and waist circumference (SMD: 0.44, 95% CI: 0.17-0.71, P<0.001).
Conclusion: This comprehensive meta-analysis provides robust evidence supporting the potential beneficial impact of probiotic-containing dairy products on BMI, weight, and waist circumference in individuals with obesity and overweight. These findings underscore the value of incorporating probiotics into dietary interventions aimed at addressing these challenging public health issues. Further research is warranted to elucidate the mechanisms underpinning these effects and to optimize the implementation of probiotics in clinical practice.
Article number: 8
Keywords: Probiotic, Dairy, Body Mass Index (BMI), Obesity, Overweight, Systematic Review, Meta-Analysis.
Article Type: Systematical Review |
Subject:
Health and safety
Received: 2022/12/28 | Accepted: 2023/01/30 | Published: 2023/09/7
Received: 2022/12/28 | Accepted: 2023/01/30 | Published: 2023/09/7
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