Volume 6, Issue 4 (2021)                   SJMR 2021, 6(4): 213-220 | Back to browse issues page

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Nateghi M R, Abbasi B, Sanaye Naderi M, Saremi A. Vertical transmission of Covid-19 disease through umbilical cord blood: A cross-sectional study. SJMR 2021; 6 (4) :213-220
URL: http://saremjrm.com/article-1-246-en.html
1- Sarem Fertility & Infertility Research Center (SAFIR), Sarem Women's Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran & Sarem Cell Research Center (SCRC), Sarem Women’s Hospital, Tehran, Iran.
2- Sarem Fertility & Infertility Research Center (SAFIR), Sarem Women's Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran & Department of Medical Genetics, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Abstract:   (283 Views)
Introduction: The new coronavirus, known as Covid-19, is a highly contagious disease that is spread through the respiratory droplets of infected people. Vertical transmission is the transmission of an infectious pathogen from mother to fetus in the prenatal and postpartum period or to the infant during the postpartum period through intrauterine placenta, contact of body fluids during childbirth or through direct contact due to postpartum breastfeeding. The aim of this study was investigation of vertical transmission of the disease through umbilical cord blood from mother to infant.
Material and methods: In this cross-sectional study, 117 patients participated in the project. All pregnant women had positive RT-PCR results for SARS-CoV-2 RNA. Nasopharyngeal and Oropharyngeal swabs were used to detect Covid-19 infection. To perform umbilical cord blood sampling, a sterile needle was inserted through the vagina and 10 cc of amniotic fluid was carefully withdrawn under sterile conditions without rupture of the membranes and leakage. Data were statistically analyzed using SPSS software version 24.
Results: Among the 5 cases (4.3%) of positive cord blood test compared to the negative cases (95.7%) of this test, there was no difference between the gender of the newborns (P>0.05). The average weight of babies with positive umbilical cord blood was 3067.46 grams and in babies with negative umbilical cord blood, it was 3588 grams, and a statistically significant difference was observed between these two groups (P<0.05). Also, there was no statistically significant difference between the two groups including positive and negative cord blood tests and parameters such as gender, height, weight, heart rate, breathing rate and Apgar scores of one and five minutes of newborns (P>0.05).
Conclusion: From this study, we can conclude that the possibility of vertical transmission of the coronavirus through cord blood is not high (nearly 4% of cases). On the other hand, the low weight of the baby at birth can indicate the transmission of this virus from mother to baby. To prove this reason, more studies should be conducted in the future and in a more large number of populations.
Article number: 3
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Article Type: Original Research | Subject: Childbirth
Received: 2021/12/26 | Accepted: 2022/01/12 | Published: 2022/11/20

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