Introduction:Celiac disease is a systemic disease with various manifestations. In past studies, the symptoms of patients in different regions have been expressed differently. Therefore, in this study, the frequency distribution of clinical symptoms in patients with Celiac disease referred to Shahid Beheshti Hospital in Kashan in the years 2015 to 2021 was investigated.
Materials and methods: In this retrospective descriptive study, the medical records of patients with definite diagnosis of Celiac disease (confirmed by through serology and pathology tests) were examined. The extracted information includes demographic variables (age and gender) and gastrointestinal symptoms (diarrhea, constipation, nausea and vomiting, anorexia, abdominal pain, flatulence, aphthous stomatitis, abdominal distension and steatorrhea) and non-gastrointestinal symptoms (anemia, arthralgia, bone pain, weight loss, seizures, hypocalcemia, weakness, infertility). The information collected with the checklist was entered into SPSS Ver.26 software and subjected to statistical analysis.
Results: In this research, 89 patients with Celiac disease (57 women, 32 men; average age 34.13±17.70 years) were evaluated. The most common clinical symptom was abdominal pain (62.9 %), followed by diarrhea (40.4%), iron deficiency anemia (29.2%), and constipation (28.1%). The most common accompanying disease was hypothyroidism (21.3%).
Discussion and Conclusion: The findings of this study show that celiac patients in Kashan suffer more from gastrointestinal symptoms such as abdominal pain, diarrhea and constipation. Among the non- Gastrointestinal symptoms, anemia was the most common finding in the patients. Celiac patients need to be screened for immunological diseases such as hypothyroidism and type 1 diabetes.
Article Type:
Original Research |
Subject:
Health and safety Received: 2023/06/28 | Accepted: 2023/09/13 | Published: 2024/03/17
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