Volume 4, Issue 1 (2019)                   SJMR 2019, 4(1): 65-69 | Back to browse issues page

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Roomande N, Saremi A, Pooladi A, Zare A. Seroepidemiological Study of Toxoplasma, Rubella, Cytomegalovirus and Varicella zoster in Women; Case Study of Sarem Women’s Hospital. SJMR. 2019; 4 (1) :65-69
URL: http://saremjrm.com/article-1-126-en.html
1- Department of Immunology, Sarem Fertility and Infertility Research Center, Sarem Women’s Hospital, Tehran, Iran
2- Sarem Fertility and Infertility Research Center, Sarem Women’s Hospital, Tehran, Iran
3- Department of Genetic, Sarem Fertility and Infertility Research Center, Sarem Women’s Hospital, Tehran, Iran
4- Sarem Fertility and Infertility Research Center, Sarem Women’s Hospital, Tehran, Iran , ahadzr@gmail.com
Abstract:   (2635 Views)
Aims: Mother-to-child transmission of Toxoplasma (Toxo), Rubella, cytomegalovirus (CMV) and varicella zoster virus (VZV) can lead to severe birth defects and even the death of the infant. Therefore, evaluation of women's immunity in childbearing age is necessary for vaccination and to prevent these infections. The aim of this study was to investigate the seroepidemiology of Toxoplasma, Rubella, CMV and VZV in women.
Materials & Methods: The present study is routine data base study. The results of pre-pregnancy tests were recorded and analyzed in the second half of 1995 in Sarem Women’s Hospital.
Findings: Toxo IgM tests were negative in 972 (99.7%) patients and only 0.3% were positive. Toxo IgG tests were negative in 97% of subjects and 3% of them. Rubella IgG test was positive in 757 cases (86.5%) and negative in 118 cases (13.5%). Rubella IgM tests were negative in all subjects who performed the test. CMV IgM tests were negative in 99.8% and only 0.2% were positive. The IgG CMV test was positive in 86.8% of patients. VZV IgM was reported in all negative cases, but VZV IgG was positive in 98.5% and negative in 1.5%. The mean age of positive cases versus negative cases except Toxo IgG did not show any significant difference (p>0/05).
Conclusion: 99.7% of women were seronegative for Toxo IgM, 99.8% for CMV IgM and all of them for Rubella IgM and VZV IgM. Also, 97% of the patients were seropositive for Toxo IgG, 86.5% for Rubella IgG, 86.8% for the CMV IgG test and 98.5% for the VZV IgG test.
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Article Type: Case Report | Subject: Reproduction
Received: 2018/06/7 | Accepted: 2019/03/16 | Published: 2019/06/15

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