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Nomanpour B, Lashgari P, Hasani M. Group B Streptococci and-Clindamycin Induced Phenotypic Resistance Pattern in Pregnant Women, Case Study of Sarem Women’s Hospital. SJMR. 2019; 4 (1) :53-57
URL: http://saremjrm.com/article-1-124-en.html
1- Department of Microbiology, Sarem Fertility and Infertility Research Center, Sarem Women’s Hospital, Tehran, Iran , nomanpoursh@gmail.com
2- Department of Microbiology, Sarem Fertility and Infertility Research Center, Sarem Women’s Hospital, Tehran, Iran
Abstract:   (2890 Views)
Aims: Streptococcus agalactiae strains or group B streptococci (GBS) are the natural flora of the anogenital area of women and are the most important cause of death in the first week of infant birth. The aim of this study was to investigate the isolated strains of group B streptococci and phenotypic resistance pattern of clindamycin induced in pregnant women.
Materials & Methods: This cross sectional-descriptive study was done on vaginal culture of 861 pregnant women. After a physical examination by a gynecologist, two vaginal swabs of vaginal discharges were taken in 1ml sterile normal saline tube and two slides were delivered to hospital laboratory for staining. The Specimens were cultured on Sheep blood agar, Eosin-methylene blue (EMB) agar and Sabouraud dextrose agar at 35±1Ċ and Chocolate agar were incubated in candle jar at the same temperature. After diagnostic tests, GBS was isolated and microbial susceptibility test was performed. Also, the Erythromycin-inducible resistances to clindamycin was measured by phenotypic D-test for the samples.
Findings: Of the 861 samples sent to the laboratory, 141 cases (16.38%) were positive for GBS. The sensitivity of GBS isolates to penicillin, cefalexin, and ceftazidime was 98.58%, 97.8% and 98.88%, respectively. There was no resistance to ampicillin and ceftriaxone in the samples, but 2.84% of them were resistant to ciprofloxacin. Clindamycin induced resistance was positive in 14.89% of pregnant women.
Conclusion: Among isolated bacteria, 16.38% of them are part of group B streptococci that 14.89% of them are clindamycin induced resistance and 38.6% of them have concurrent resistance to erythromycin and clindamycin.
Full-Text [PDF 471 kb]   (496 Downloads)    
Article Type: Brief Communication | Subject: Reproduction
Received: 2018/06/7 | Accepted: 2019/03/16 | Published: 2019/06/15

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