Volume 3, Issue 3 (2018)                   SJMR 2018, 3(3): 165-168 | Back to browse issues page

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Rahimi M, Saadatnia G, Salehian P. Presence of Group B Streptococcus in the Placenta of Infected Pregnant Women. SJMR 2018; 3 (3) :165-168
URL: http://saremjrm.com/article-1-71-en.html
Presence of Group B Streptococcus in the Placenta of Infected Pregnant Women
M. Rahimi1 , G. Saadatnia * 2, P. Salehian3
1- Basic Science Faculty, Science and Research Branch, Islamic Azad University, Tehran, Iran
2- Biotechnology Research Institute, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran , gitasaadat@gmail.com
3- Dr. Salehian medical laboratory, Tehran, Iran
Abstract:   (5303 Views)

Aims: Group B Streptococcus (GBS) is one of the most important causes of neonatal infections. This bacterial pathogen is associated with preterm birth and neonatal mortality. This study was aimed to evaluate the presence of GBS in the placenta of infected pregnant women.
Materials & Methods: This analytical case-control study was conducted on pregnant patients referred to Sarem women’s hospital (Tehran, Iran) for delivery during 2013-2014. A total of 80 formalin-fixed and paraffin-embedded placenta tissues were studied, including 55 samples from GBS positive patients (30 samples with chorioamnionitis and 25 without chorioamnionitis) and 25 samples from GBS negative subjects with chorioamnionitis as the controls. The presence of GBS for each sample was tested by polymerase chain reaction (PCR) and 1.5% agarose gel electrophoresis.
Finding: GBS genomic DNA was not detected in any sample from the placenta tissue.
Conclusion: Group B Streptococcus is not present in the placenta of the women infected with GBS (with or without amniotic membrane inflammation).

Keywords: Group B Streptococcus, Molecular Diagnostic Techniques, Placenta, Pregnancy
Full-Text [PDF 379 kb]   (1427 Downloads)    
Article Type: Original Research | Subject: Reproduction
Received: 2017/04/30 | Accepted: 2017/10/12 | Published: 2018/11/22
English Expanded Abstract [HTML 16 KB]  (88 Download)
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