Volume 8, Issue 1 (2023)                   SJMR 2023, 8(1): 1-4 | Back to browse issues page


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Behjati F. The Application of Personalized Medicine in Female Cancers. SJMR 2023; 8 (1) : 1
URL: http://saremjrm.com/article-1-286-en.html
Sarem Gynecology, Obstetrics and Infertility Research Center, Sarem Women’s Hospital, Iran University of Medical Science (IUMS), Tehran, Iran. &Sarem Cell Research Center (SCRC), Sarem Women’s Hospital, Tehran, Iran.
Abstract:   (799 Views)
Personalized medicine, also known as “precision medicine,” is the science of individualizing cancer care by treating tumors based on their genetic makeup rather than their location of origin. Personalized medicine or precision medicine was first defined for management of cancer patients with the idea that information of patient’s genes, proteins, metabolites and environment can be applied for its individualized management and it encompasses prevention, screening, diagnosis, prognosis, treatment, follow up, detection of recurrence and categorization of patient to defined subgroups for more effective treatment. Current evidence suggests the relative success of this approach in cancer patients. The development and implementation of personalized medicine required a set of objectives and valid biomarkers through genomics, transcriptomics, and proteomics and metabolomics knowledge of huge sample cohorts regarding confounding factors, such as age, gender, habits, diet, and environment. Personalized medicine in reproductive medicine is still in its nonage since it is not yet a fully strengthened mature arena. Reproductive medicine is at the preliminary stage of discovering and validating genomic, protein and metabolite biomarkers. Perhaps what is currently being offered as personalized treatment of infertile patient is more based on “the best expert opinion of the attending clinician” than “the best evidence-based data available”.
Article number: 1
Full-Text [PDF 263 kb]   (432 Downloads)    
Article Type: Editorial | Subject: Women Diseases
Received: 2023/09/13 | Accepted: 2023/09/13 | Published: 2023/09/13

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