Volume 7, Issue 1 (2022)                   SJMR 2022, 7(1): 29-39 | Back to browse issues page

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Suri F, Alinia C, Taghizadeh S, Merajipour T, Mohammadimadi S F. Clinical and economic analysis of the policy to prevent the birth of Down syndrome fetuses and evaluation of clinical ophthalmic manifestations in affected individuals. SJMR 2022; 7 (1) : 4
URL: http://saremjrm.com/article-1-257-en.html
1- Assistant Professor, Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran & Secretary of Inherited Blinding Diseases Working Group, Department of Eye Health and Prevention of Blindness, Ministry of Health, Treatment and Medical Education, Tehran, Iran
2- Assistant Professor of Health Economics, Department of Health Management and Economics, School of Public Health, Urmia University of Medical Sciences, Urmia, Iran & Associate Researcher of Community Ophthalmology Research Center, Farabi Hospital, Tehran, Iran.
3- Postdoctoral Researcher, Translational Ophthalmology Research Center, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
4- Expert of Eye Health and Prevention of Blindness, Ministry of Health, Treatment and Medical Education, Tehran, Iran.
5- Associate Researcher of Community Ophthalmology Research Center, Farabi Hospital, Tehran, Iran & Professor of Cornea & External Eye Diseases, Knowledge Management Unit, Translational Ophthalmology Research Center, Farabi Hospital, Tehran University of Medical Sciences.
Abstract:   (985 Views)
Introduction: Down syndrome, or trisomy 21, is a genetic disorder that without preventive intervention, about 1,000 cases of Down syndrome are expected annually among live births in Iran. More than eighty clinical features have been described in people with Down syndrome. Eye diseases occur in 60% of Down syndrome patients. These problems negatively affect the quality of life and cause complexities and issues in educational and therapeutic systems.
Material and methods: In this study, different aspects of Down syndrome with emphasis on ocular complications from 1993 to 2022, and calculating the economic burden of down syndrome by using the cost method of the disease have been performed.
Results & Discussion: Based on the expenses of the year 1399, each person with Down syndrome, on average, imposes more than 368 million Tomans annually on society during its lifetime. Also, if preventive policies are implemented with a 90% success rate and >1000 Down's syndrome births annual rate, about 381.6 billion Tomans can be saved annually. Hence, the Department of Eye Health and Prevention of Blindness, Ministry of Health and Medical Education of Iran strongly recommend taking conventional diagnostic-medical action to prevent the birth of a child with Down syndrome.
Article number: 4
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Article Type: Original Research | Subject: Women Diseases
Received: 2022/05/13 | Accepted: 2022/05/31 | Published: 2023/02/12

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