Introduction: Amniotic fluid embolism (Anaphylactoid Syndrome of Pregnancy) is a rare and unpredictable complication of pregnancy that occurs during or post-parturition. This complication occurs when amniotic fluid enters mother blood, which this condition is rare and its main symptom is cardiopulmonary arrest. Because maternal mortality associated with this complication is so high, early detection and prompt treatment are important for the improvement of prognosis.
Case presentation:  A 37-year-old pregnant woman, gravida 2 para 2, experienced cardiac and respiratory arrest at the end of the cesarean operation and 45 minutes after spinal anesthesia and then baby exhaust. The baby was healthy. Mother had a height of 170 cm, weight 117 kg, and BMI of more than 40 that CPR was started promptly and after 10 minutes of necessary evaluations, the patient had vital signs and sinus rhythm. The patient was discharged in good general condition.
Conclusion: Initial supportive care is important if amniotic fluid embolism (AFE) is suspected. Early diagnosis and aggressive management of the patient with cardiopulmonary resuscitation will be associated with increased survival and reduced morbidity and mortality.

Keywords: Amniotic Fluid Embolism (AFE), Anaphylactoid Syndrome of Pregnancy (ASP), Cardiopulmonary Arrest, Cesarean, Case Report.

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