Volume 3, Issue 4 (2019)
SJMR 2019, 3(4): 19-23 |
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1- Sarem Fertility & Infertility Research Center (SAFIR), Sarem Women’s Hospital, Tehran, Iran
2- *“Sarem Fertility & Infertility Research Center (SAFIR)” and “Sarem Cell Research Center (SCRC)”, Sarem Women’s Hospital, Tehran, Iran , Saremiat@yahoo.com
3- *“Sarem Fertility & Infertility Research Center (SAFIR)” and “Sarem Cell Research Center (SCRC)”, Sarem Women’s Hospital, Tehran, Iran
2- *“Sarem Fertility & Infertility Research Center (SAFIR)” and “Sarem Cell Research Center (SCRC)”, Sarem Women’s Hospital, Tehran, Iran , Saremiat@yahoo.com
3- *“Sarem Fertility & Infertility Research Center (SAFIR)” and “Sarem Cell Research Center (SCRC)”, Sarem Women’s Hospital, Tehran, Iran
Abstract: (6418 Views)
Aims: Preterm labor is the most common cause of mortality among neonates. The risk of spontaneous preterm labor is increased due to various maternal factors. Therefore, the objective of this study was to investigate the maternal factors involved in preterm labor.
Materials & Methods: This cross-sectional study as a descriptive-analytic and retrospective study was conducted on 2432 women referred to Sarem women’s hospital in 2013. The patients' data including demographic information and risk factors for preterm labor were collected by a researcher-made-questionnaire. The data were analyzed by Mann-Whitney U, Fisher's exact and Chi square tests using SPSS 22 software.
Findings: The prevalence of preterm labor was found as 237 (9.75%). The maternal factors including body mass index (BMI), maternal age (more than 35 years), history of thyroid disease, intrauterine fetal death (IUFD), premature rupture of membranes (PROM), preeclampsia, parity, two or multiple pregnancies and abnormal volume of amniotic fluid showed significant correlation with the occurrence of spontaneous preterm labor (P <0.05). However, the other factors including hypertension history before pregnancy, history of abortion, history of diabetes and ectopic pregnancy did not show statistically significant correlation with preterm labor (P>0.05).
Conclusion: Maternal factors including BMI, maternal age, thyroid disease, IUFD, PROM, preeclampsia, parity, two or multiple pregnancies and abnormal volume of amniotic fluid can influence the occurrence of spontaneous preterm labor.
Article Type: Original Research |
Received: 2017/08/20 | Accepted: 2017/12/21 | Published: 2019/01/4
Received: 2017/08/20 | Accepted: 2017/12/21 | Published: 2019/01/4
References
1. Lawn JE, Wilczynska-Ketende K, Cousens SN. Estimating the causes of 4 million neonatal deaths in the year 2000. Int J Epidemiol. 2006;35(3):706-18. [Link] [DOI:10.1093/ije/dyl043] [PMID]
2. Ratzon R, Sheiner E, Shoham Vardi I. The role of prenatal care in recurrent preterm birth. Eur J Obstet Gynecol Reprod Biol. 2011;154(1):40-4. [Link] [DOI:10.1016/j.ejogrb.2010.08.011] [PMID]
3. Beck S, Wojdyla D, Say L, Betran AP, Merialdi M, Requejo JH, et al. The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity. Bull World Health Organ. 2010;88(1):31-8. [Link] [DOI:10.2471/BLT.08.062554] [PMID] [PMCID]
4. Sibai BM, Caritis SN, Hauth JC, MacPherson C, VanDorsten JP, Klebanoff M, et al. Preterm delivery in women with pregestational diabetes mellitus or chronic hypertension relative to women with uncomplicated pregnancies. Am J Obstet Gynecol. 2000;183(6):1520-4. [Link] [DOI:10.1067/mob.2000.107621] [PMID]
5. Kramer MS, Wilkins R, Goulet L, Séguin L, Lydon J, Kahn SR, et al. Investigating socio‐economic disparities in preterm birth: Evidence for selective study participation and selection bias. Paediatr Perinat Epidemiol. 2009;23(4):301-9. [Link] [DOI:10.1111/j.1365-3016.2009.01042.x] [PMID]
6. Kramer MS, Goulet L, Lydon J, Séguin L, McNamara H, Dassa C, et al. Socio‐economic disparities in preterm birth: causal pathways and mechanisms. Paediat Perinat Tpidemiol. 2001;15(2):104-23. [Link] [DOI:10.1046/j.1365-3016.2001.00012.x]
7. Heaman M, Kingston D, Chalmers B, Sauve R, Lee L, Young D. Risk Factors for Preterm Birth and Small‐for‐gestational‐age Births among Canadian Women. Paediat Perinat Epidemiol. 2013;27(1):54-61. [Link] [DOI:10.1111/ppe.12016] [PMID]
8. Mercer B, Goldenberg RL, Das A, Moawad A, Iams JD, Meis PJ, et al. The preterm prediction study: a clinical risk assessment system. Am J Obstet Gynecol. 1996;174(6):1885-95. [Link] [DOI:10.1016/S0002-9378(96)70225-9]
9. Palomar L, DeFranco EA, Lee KA, Allsworth JE, Muglia LJ. Paternal race is a risk factor for preterm birth. Am J Obstet Gynecol. 2007;197(2):152.e1-7. [Link] [DOI:10.1016/j.ajog.2007.03.035] [PMID]
10. Heaman MI, Blanchard JF, Gupton AL, Moffatt ME, Currie RF. Risk factors for spontaneous preterm birth among aboriginal and non‐aboriginal women in Manitoba. Paediatr Perinatal Epidemiol. 2005;19(3):181-93. [Link] [DOI:10.1111/j.1365-3016.2005.00644.x] [PMID]
11. Shin D, Song WO. Prepregnancy body mass index is an independent risk factor for gestational hypertension, gestational diabetes, preterm labor, and small-and large-for-gestational-age infants. J Maternal-Fetal Neonatal Med. 2015;28(14):1679-86. [Link] [DOI:10.3109/14767058.2014.964675] [PMID]
12. Verma I, Avasthi K, Berry V. Urogenital Infections as a Risk Factor for Preterm Labor: A Hospital-Based Case–Control Study. J Obstet Gynecol India. 2014;64(4):274-8. [Link] [DOI:10.1007/s13224-014-0523-6] [PMID] [PMCID]
13. Gilbert ES. Manual of high risk pregnancy and delivery. 5th edition. Amsterdam: Elsevier Health Sciences; 2010. [Link]
14. Afrakhteh M, Ebrahimi S, Valaie N. Prevalence of preterm delivery and its related factors in females referring to Shohada Tajrish Hospital. Pejouhandeh. 2003;7(4):341-4. [Persian] [Link]
15. Chan BC P, Lao TT H. Effect of parity and advanced maternal age on obstetric outcome. Int J Gynecol Obstet. 2008;102(3):237-41. [Link] [DOI:10.1016/j.ijgo.2008.05.004] [PMID]
16. Martius JA, Steck T, Oehler MK, Wulf K-H. Risk factors associated with preterm (< 37+ 0 weeks) and early preterm birth (< 32+ 0 weeks): Univariate and multivariate analysis of 106 345 singleton births from the 1994 statewide perinatal survey of Bavaria. Eur J Obstet Gynecol Reprod Biol. 1998;80(2):183-9. [Link] [DOI:10.1016/S0301-2115(98)00130-4]
17. Covarrubias L, Aguirre G, Chapuz J, May AL, Velázquez JD, Eguiluz ME. Maternal factors associated to prematurity. Ginecol Obstet Méx. 2008;76(9):526-36. [Link] [PMID]
18. Swingle HM, Colaizy TT, Zimmerman MB, Morriss FH Jr. Abortion and the risk of subsequent preterm birth: a systematic review with meta-analyses. J Reprod Med. 2009;54(2):95-108. [Link] [PMID]
19. Khalaji Nia Z, Sadeghi Moghaddam P. Prevalence and maternal risk factors of preterm laboring in Qom, 2007. Qom Univ Med Sci J. 2011;5(1):30-6. [Link]
20. Khadem N, Farhat A, Ghomian N, Ibrahimzadeh S. Prevalence of preterm labor and it's complications in neonates of women with preeclampsia-eclampsia in Emam Reza Hospital. J Ardabil Univ Med Sci. 2007;7(4):368-74. [Link]
21. Mohammadian S, Vakili M, Tabandeh A. Survey of related factors in prematurity birth. J Gilan Univ Med Sci. 2000;9(33-34):117-22. [Persian] [Link]
22. Hedderson MM, Ferrara A, Sacks DA. Gestational diabetes mellitus and lesser degrees of pregnancy hyperglycemia: Association with increased risk of spontaneous preterm birth. Obstet Gynecol. 2003;102(4):850-6.
https://doi.org/10.1097/00006250-200310000-00030 [Link] [DOI:10.1016/S0029-7844(03)00661-6]
23. Hickok DE, Hollenbach KA, Reilley SF, Nyberg DA. The association between decreased amniotic fluid volume and treatment with nonsteroidal anti-inflammatory agents for preterm labor. Am J obstet gynecol. 1989;160(6):1525-31. [Link] [DOI:10.1016/0002-9378(89)90880-6]
24. Harman CR. Amniotic fluid abnormalities. Semin Perinatol. 2008;32(4):288-94. [Link] [DOI:10.1053/j.semperi.2008.04.012] [PMID]
25. Astolfi P, Zonta L. Risks of preterm delivery and association with maternal age, birth order, and fetal gender. Hum Reprod. 1999;14(11):2891-4. [Link] [DOI:10.1093/humrep/14.11.2891]
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