Ghodrati N, Abbasi B, Abbasgholi H, Tavoosi Z, Bushehri A, Rastgookoorandeh M. Hemophagocytic Lymphohistiocytosis in an Adult Presenting with Sore Throat and Fever. SJMR 2022; 7 (3) :151-155
URL:
http://saremjrm.com/article-1-272-en.html
1- Department of oncology, Shahid Bahonar Hospital, Alborz University of Medical Sciences, Karaj, Iran
2- Department of Medical Genetics, National Institute of Genetic Engineering and Biotechnology, Tehran
3- Sarem gynecology, Obstetrics and Infertility Research Center, Sarem Women's Hospital, Iran University of Medical Sciences (IUMS), Tehran
4- Ahram Hospital, Bushehr University of Medical Sciences, Bushehr, Iran
Abstract: (441 Views)
Hemophagocytic Lymphohistiocytosis (HLH) is a rare but potentially fatal syndrome of immune hyperactivation. The HLH-2004 criteria is a standard guide for the diagnosis of HLH. We report the case of a 48-year-old female who presented with a sore throat, fever, weakness, and lethargy. Initial laboratory tests revealed pancytopenia. A bone marrow aspirate was performed, which revealed hemophagocytosis. The patient fulfilled the HLH-2004 criteria. The present study tries to raise awareness about the proper diagnosis of Epstein-Barr virus (EBV) and to notify clinicians about one of the rarest complications of this disease (HLH).
Article number: 3
Article Type:
Case Report |
Subject:
Health and safety Received: 2022/10/12 | Accepted: 2022/10/27 | Published: 2023/04/10